Independent RNA-seq analysis of GSE280564 examining transcriptional reprogramming of normal fibroblasts (HUF) into cancer-associated fibroblasts (CAFs) via tumor-derived conditioned media versus primary tumor-derived CAFs. Built on a custom Nextflow DSL2 pipeline (FastQC, Fastp, STAR, featureCounts) run on GCP Batch. Identifies a core CAF transcriptional signature shared across reprogramming models, and introduces a novel "resister gene" analysis revealing that conditioned media fails to recapitulate ~60% of the transcriptional changes seen in genuine tumor-derived CAFs — particularly developmental identity programs (HOX genes) that may be epigenetically protected from reprogramming.

Nesta análise de dados, avaliamos as ondas de calor identificadas sob a ótica de decomposição de multiescala por ondaletas.

Laplace equation 2D using R

Digitised Plot 1 data from the biomass ranking survey done by Greg Forsyth in 1987 in the Swartboskloof. Done and prepared by Jason Ross

Exercícios propostos para planilha propostas (ChiTeste) em Testes Estatísticos

Digitised version of data collected by Greg Forsyth in the Swartboskloof at plot 10 in 1987. Prepared by Jason Ross

Este documento presenta un workflow reproducible para modelar la distribución potencial de una especie mediante un enfoque escalonado. El análisis separa dos preguntas distintas: primero identifica la señal ambiental regional con predictores bioclimáticos de escala gruesa; luego refina la predicción en un área local usando predictores de mayor resolución espacial.

Atividade de Probabilidade e Amostragem