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Analysis using R
The training aims to introduce model applications commonly used in the analysis of data from studies. We seek to give sufficient background so that you better understand the types of analyses that can be implemented for designed experiments. We give practical examples and hands-on applications so that you can experience how these analyses are conducted. We introduce a framework that will easily extend to more complex structures in the models. We will assume some underlying knowledge of mathematical concepts and statistical notation.
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TUGAS PROJEK ETS NOVA
DA Lecture - Topic 3A
Unit 9 Project
Part 2 to the GSE289903 study on Hodgkins and Hodgkins with EBV and HIV using machine learning to distinguish genes with random forest
In this study we categorize the genes, add in genes from other studies recently part of our projects, get the subtypes and find out if the genes that are specific to the study top genes, the top fold change genes for EBV and HIV in Hodgkins lymphoma, or the genes relative to the study in finding specificity to tumor mutation burden or tmb, immune checkpoint inhibitor, HIV specific, and other combinations to predict the class samples in a 3 class model for diagnosis type, then in a 5 class model of subtype cellularity. The genes specifically selected from this set scored 100% accuracy in subtype prediction of Nodular Sclerosis or Mixed Cellularity and found in 2 different gene feature sets as predictors that the NA sample was the Nodular Sclerosis as a prediction. The part 1 is added to the end of this part 2. For class type, the best performing features were not the top fold change genes but all 35 genes, or top 5 genes of the study in predicting the Hodgkins or Hodgkins with EBV but not in Hodgkins with EBV and HIV like the top 5 ranked tumor mutational burden found them in more mutations within the HIV samples.